A highly conserved WDYPKCDRA epitope in the RNA directed RNA polymerase of human coronaviruses can be used as epitope-based universal vaccine design.
Identifieur interne : 001714 ( Main/Exploration ); précédent : 001713; suivant : 001715A highly conserved WDYPKCDRA epitope in the RNA directed RNA polymerase of human coronaviruses can be used as epitope-based universal vaccine design.
Auteurs : Refat Sharmin ; Abul Bashar Mir Md Khademul Islam [Bangladesh]Source :
- BMC bioinformatics [ 1471-2105 ] ; 2014.
Descripteurs français
- KwdFr :
- MESH :
- enzymologie : Coronavirus.
- immunologie : Coronavirus, Protéines virales, RNA replicase.
- Algorithmes, Alignement de séquences, Humains, Protéines virales, RNA replicase, Séquence conservée, Séquence d'acides aminés, Vaccins antiviraux, Épitopes.
English descriptors
- KwdEn :
- MESH :
- chemical , chemistry : Epitopes, RNA Replicase, Viral Proteins.
- enzymology : Coronavirus.
- immunology : Coronavirus, RNA Replicase, Viral Proteins.
- Algorithms, Amino Acid Sequence, Conserved Sequence, Humans, Sequence Alignment, Viral Vaccines.
Abstract
Coronaviruses are the diverse group of RNA virus. From 1960, six strains of human coronaviruses have emerged that includes SARS-CoV and the recent infection by deadly MERS-CoV which is now going to cause another outbreak. Prevention of these viruses is urgent and a universal vaccine for all strain could be a promising solution in this circumstance. In this study we aimed to design an epitope based vaccine against all strain of human coronavirus.
DOI: 10.1186/1471-2105-15-161
PubMed: 24884408
Affiliations:
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Le document en format XML
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From 1960, six strains of human coronaviruses have emerged that includes SARS-CoV and the recent infection by deadly MERS-CoV which is now going to cause another outbreak. Prevention of these viruses is urgent and a universal vaccine for all strain could be a promising solution in this circumstance. In this study we aimed to design an epitope based vaccine against all strain of human coronavirus.</div></front></TEI><affiliations><list><country><li>Bangladesh</li></country></list><tree><noCountry><name sortKey="Sharmin, Refat" sort="Sharmin, Refat" uniqKey="Sharmin R" first="Refat" last="Sharmin">Refat Sharmin</name></noCountry><country name="Bangladesh"><noRegion><name sortKey="Islam, Abul Bashar Mir Md Khademul" sort="Islam, Abul Bashar Mir Md Khademul" uniqKey="Islam A" first="Abul Bashar Mir Md Khademul" last="Islam">Abul Bashar Mir Md Khademul Islam</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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